Saturday , 28 November 2020

Blog Archives

Photoperiod regulates the daily profiles of Tryptophan Hydroxylase-2 gene expression the raphe nuclei of rats

Tryptophan hydroxylase-2 mRNA (TPH, the rate limiting enzyme in 5-HT synthesis) expression levels display circadian variations in the median and dorsal raphe nuclei. This circadian pattern is under the control of the suprachiasmatic nuclei (SCN), the master clock. Photoperiodic cue is encoded by the SCN which convey the seasonal message to target sites. In the present study, we have investigated …

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“SUPPLEMENTATION OF ZINC IN ACUTE AND CHRONIC HEAT STRESS ON ANTIOXIDANT CHANGES IN WISTAR ALBINO RATS”

ABSTRACT: Introduction: Heat stress is a major health burden with potential health out-comes. Oxidative stress is a metabolic dysfunction that carries oxidative damage of cells and tissues. Zinc is a co-factor against oxidative stress. Aim: The present study was done to evaluate the Supplementation of zinc in acute and chronic heat stress on antioxidant changes in wistar albino rats. Methodology: …

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Bone mineral density and its correlation with Vitamin D status in healthy adults of Manipur – A cross-sectional study

The levels of vitamin D have an important effect on bone mass in young and old. Hypovitaminosis D adversely affects calcium metabolism, osteoblastic activity, matrix ossification, bone remodeling, and hence bone density. Objective: The present study was conducted to determine the status of serum 25(OH)D and BMD of healthy adult men in Manipur and also to find out the relationship …

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The potential effect of pandan wangi leaf “pandanus amaryllifolius roxb.’’ extract from Indonesia as time sleep inductor

Sleep plays a role in restoring the body’s biochemical and physiological processes which decrease when awake. People is not familiar yet with sleep disturbances, so they rarely seek help. Sleep disturbances can cause family problems and are at risk of fatal traffic accidents. Fragant Pandan leaves (Pandanus amaryllifolius Roxb.) contains alkaloids, saponins and flavonoids which can provide a hypnotic sedative …

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Public Health concern for a Nipah Virus disease

Nipah virus (NiV) is a pathogenic paramyxovirus that has been responsible for sporadic outbreaks of respiratory and encephalitic disease in tropical countries. Elevated case mortality rate has also been connected with recent outbreaks in India (Kerala), Malaysia and Bangladesh. The virus generally infects animals like pigs and bats, but they do not show any symptoms of NiV.  The mortality rate …

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Pulmonary function tests in petrol pump workers exposed for three years to petrol/diesel fumes in Mathura District Uttar Pradesh

Background: Occupational and environmental exposure to petroleum refinery products poses a great threat to human health and petrol pump workers by virtue of their occupation are continuously exposed to petroleum gases and petroleum products. This community is generally neglected regarding their health. Aims and objectives: This study aimed to assess and compare the Pulmonary functions of petrol pump workers with …

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Evaluating serum C-reactive protein level in patients with chronic obstructive pulmonary disease – A cross-sectional study

Abstract Patients with the chronic obstructive pulmonary disease have ongoing systemic inflammation, which can be assessed by measuring serum  C- reactive protein. Objective: To explore whether CRP could be used as an independent predictor of disease outcome in COPD. Methods: A cross-sectional study was conducted among 50 COPD patients attending Respiratory Medicine outpatient services in the Regional Institute of Medical …

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Cutaneous Complications in Macrolide Prescribing in Pediatrics

Cutaneous adverse reactions are very common adverse effect of post antibiotic therapy. Cutaneous adverse reactions include skin lesions in the form of rashes urticaria, maculopapular rashes, eythema multiforme, stevens-johnson syndrome and toxic epidermal necrolysis. However macrolides, generally considered safer in this regard, are frequently used to treat both adult and childhood infections, with favorable outcomes. Cutaneous manifestations of this class …

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Tibial Fracture in an Elderly Female Patient of Rheumatoid Arthritis: A Preventable Iatrogenic Injury

Oral systemic glucocorticoids widely used in the medical practice to treat various diseases like asthma, systemic connective tissue diseases, other autoimmune diseases and in transplantology, are considered the main cause of secondary and iatrogenic osteoporosis. The pathogenesis of glucocorticoid induced bone loss is multifactorial and complex. The exact mechanism remains undefined. The present report describes a case of 65 yr …

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