To counter oxidative stress, cells constitutively express enzymes that detoxify the reactive oxygen species and repair the damage. An antioxidant is any substance that when present at low concentrations compared to those of an oxidizable substrate significantly delays or prevents oxidation of that substrate. The antioxidant enzymes are major cell defense against acute oxygen toxicity. The functions of these antioxidant …Read More »
RANDOMIZED COMPARISON OF EFFICACY, DURATION OF ACTION, ADVERSE REACTIONS AND COST EFFECTIVENESS OF PENTAZOCINE AND TRAMADOL ON RELIEF OF POST OPERATIVE PAIN
Background: Many options are available for the treatment of postoperative pain. By considering patients’ preferences and making an individualized assessment of the risks and benefits of each treatment modality, the clinician can optimize the postoperative analgesic regimen for each patient. Material method: Female patients of age between 30 to 60 years undergoing elective abdominal and vaginal hysterectomies were included in …Read More »
Effects of alpha, beta momorcharin fruit extract with the combination of paclitaxel in the treatment of glioma cancer in-vivo.
The vegetable Momordica charantia L., (family: Cucurbitaceae) is a scientific name of the plant and its fruit. It is also known by other names, for instance in the USA it is known as Bitter gourd or balsam pear while its referred to as the African cucumber in many African countries. M.charantiais believed to posse’s anti-carcinogenic properties and it can modulate …Read More »
EFFECT OF AFLATOXIN M1, “A HYDROXYLATED METABOLITE OF B1” ON SPERM CELL QUALITY OF ADULT MALE WISTAR RATS.
The effect of aflatoxin on reproductive health takes a systematic approach as it indicates that a significant number of people living in the third world regions are exposed to these toxins due to the poor storage of grains. To expose the effects of aflatoxin M1 a hydroxylated metabolite of aflatoxin M1 Twenty four Adult male Wister rats were acclimatized and …Read More »
Conceptual, sociological and materialistic view of innovation-translation dynamics in medicine: The need and directions for a novel multi-pronged initiative
The recent decades have witnessed overwhelming advancements in medical technologies and the quality of healthcare. A vast majority of the advancements which are capable of revolutionising healthcare still remain dormant within laboratories which is certainly due to the tardive translation and assimilation of these innovations. Innovation-translation is explained by an over-simplified linear model which provides the users with just two …Read More »
Phytochemistry, Anthelmintic study of herbaceous aerial part of Kallstroemia pubescens (G. Don) & Review of Novel Effects of Diosgenin: A Plant Derived Steroid
The genus is named after A. Kallstroem who lived in the 18th century. Diosgenin is an aglycone of the steroidal saponin, dioscin in yam and is a principal raw material for the industrial production of steroid drugs. It belongs to triterpene group and is of great interest to the pharmaceutical industry because of its estrogenic effect on the mammary gland. …Read More »
Effects of α, β momorcharin extract of momordica charantia in intracellular free calcium on cancer cell lines.
The Momordica charantia L., (family: Cucurbitaceae) is a scientific name of the plant and its fruit. It is also known by other names, for instance in the USA it is known as Bitter gourd or balsam pear while its referred to as the African cucumber in many African countries. This study was specifically designed to investigate the cellular mechanisms whereby alpha, beta momorcharin …Read More »
GANDHIAN PRINCIPLES ON HEALTH: EVIDENCES, RELEVANCE AND IMPLICATIONS IN THE MODERN CONTEXT OF HEALTH
Mohan Das Karamchand Gandhi, popularly known as Mahatma Gandhi is one of the greatest visionaries who is known for his anti-imperialistic views and strong political strategies. Right from his childhood till his last breath, he had a keen interest in practising medicine. In spite of the odds going against him to pursue a formal medical degree, he practiced medicine throughout …Read More »
Objective: To analyse the rationality of various FDCs used in the treatment Diabetes Mellitus and to find out the irrational FDCs existing in Indian market. Material and Methods: Study Design: Analytical study. Data on FDC’s available in the Indian market was collected from Current Index of Medical Specialities (CIMS) and Monthly Index of Medical Specialities (MIMS) and their rationality was analysed …Read More »