Document
Metadata
Title
GENES BIOMARKERS IN AUTISM: BRAIN DEVELOPMENT AND FUNCTION
Authors
Dahmayanti Saridewi, Dahrizal
Description
Autism is childhood neuropsychiatric disorder despite exhibiting high heritability and has largely eluded efforts to identify specific genetic variants of biomarkers. This neuropsychiatric disorder is characterized by social and communicative deficits and ritualistic-repetitive behaviour that are detectable in early childhood. It has been reported that some candidate genes has been found in autism children brains. The candidate genes include aspects of neurogenesis, neuronal migration, maturation, differentiation, and degeneration. Some of researchers had reported the effects of the mutated and sufficiency of the candidate genes in autism brain which believed that might involved in the mechanism and causes deficit in social behaviour language impairment and repetitive behaviour. In this review, we will summarize the gene candidate which found in autism children brains and their effect of their cognitive function.
Keywords: Autism; Gene biomarkers; Brain development.
Source
International Journal of Clinical and Biomedical Research; Volume 4, Issue 2; April 2018; 74-79
Publisher
Sumathi Publications
Type
info:eu-repo/semantics/article
Date
2018-04-15
Format
application/pdf
Language
eng
Rights
Copyright (c) 2018 Dahrizal Dahmayanti Saridewi, Abdul Karim Norwahidah