LIPID PEROXIDATION AND LIPOPROTEIN CONCENTRATIONS IN CORD BLOOD OF PREGNANCY INDUCED HYPERTENSION

Description

Hypertensive disorders complicating pregnancy are common and form one of the deadly triad, along with hemorrhage and infection that contribute greatly to maternal morbidity and mortality. The present study was undertaken to determine the changes in lipid peroxidation and lipoprotein concentrations in cord blood of pregnancy induced Hypertensive patients. The MDA  levels in cord blood of Pregnancy induced Hypertension patients. MDA levels were significantly elevated (p < 0.001). Supporting  a concept of elevated oxidative stress in fetal circulation in pregnancy induced hypertension. Hydrolysis of Tgs compared with normal gestation, resulting in impaired Generation of LDL particles from Tg rich lipoproteins. Plasma Uric acid  in Pregnancy induced  Hypertension cases were raised significantly in comparison with controls (p < 0.001).
KEYWORDS: Lipid peroxidation; Pregnancy induced hypertension; Lipoprotiens.