CORRELATION OF PROLACTIN LEVELS WITH THYROID HORMONE LEVELS IN THYROID DISORDERS, INFERTILITY AND MENSTRUAL DISORDERS
Nikhil P, Shidhaye
Introduction: Prolactin and Thyroid hormones are regulated through an interrelated pathway. The increased level of TRH in hypothyroidism stimulates the release of prolactin. Prolactin and thyroid disorders are associated in a variety of conditions. Aims: To find if any correlation exists between Prolactin and Thyroid hormone levels in thyroid disorders. Methods: It was an observational, retrospective study. Serum levels of T3, T4, TSH and Prolactin were estimated by ELISA kits. The data was collected from registers and analyzed for correlation. Results: A significant proportion of hyperprolactinemia cases are Euthyroid. Hyperprolactinemia is associated with both hypothyroidism as well as hyperthyroidism. It is more prevalent in hypothyroid cases. Prolactin has a positive correlation with TSH in both hyperthyroidism and hypothyroidism. Conclusion: Prolactin has a positive correlation with TSH in both hyperthyroidism and hypothyroidism. Both prolactin and thyroid hormone levels should be estimated in cases of infertility, menstrual disturbances and thyroid disorders.
Keywords: Hyperprolactinemia; Hyperthyroidism; Hypothyroidism.
International Journal of Clinical and Biomedical Research; Volume 4, Issue 2; April 2018; 12-15
Copyright (c) 2018 Shidhaye Nikhil P, Pratinidhi SA, Savla Khushboo S, Zope RD, Sontakke Alka