“SUPPLEMENTATION OF ZINC IN ACUTE AND CHRONIC HEAT STRESS ON ANTIOXIDANT CHANGES IN WISTAR ALBINO RATS”

Journal: International Journal of Current Research in Physiology and Pharmacology

Article type: Research Article

Published: 2020-03-30

Volume: 4; Issue: 1; Pages: 14-16

ISSN: 2456-3891

DOI: 10.31878/ijcrpp.2020.41.04

Article URL: https://journals.sumathipublications.com/article/article-1782845628813-127970382

PDF: https://journals.sumathipublications.com/article/article-1782845628813-127970382.pdf

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Authors

  1. Antony Madhuri Bedadala
    assistant professor in physiology
  2. Anthony David M
    PROFESSOR AND HOD IN PHYSIOLOGY

Abstract

ABSTRACT: 
 Introduction: Heat stress is a major health burden with potential health out-comes. Oxidative stress is a metabolic dysfunction that carries oxidative damage of cells and tissues. Zinc is a co-factor against oxidative stress. Aim: The present study was done to evaluate the Supplementation of zinc in acute and chronic heat stress on antioxidant changes in wistar albino rats. Methodology : 36 Wistar albino rats were selected for the study. They were divided into 2 Groups. Group A was acutely and Group B was chronically heat stressed rats and both were zinc pretreated. The Enzymatic and Non enzyme activity in them were estimated. 
 Results: After acute and chronic heat stress, i) there was a significant increase (P <0.001) in lipid peroxidation activity. ii) Enzymatic and Non-enzymatic antioxidants were reduced (P < 0.001) iii) Rats pretreated with zinc showed a decrease (P< 0.001) in lipid peroxidation and increase (P < 0.001) in enzymatic antioxidants (P < 0.001) and Non enzymatic antioxidants. 
 Key Words : antioxidants, heat stress, wistar albino rats

Keywords

antioxidants; heat stress; wistar albino rats

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