Formulation and evaluation of herbal paediatric edible jelly of Breynia vitis-idea for helminthic infections

Authors

1. Gopikrishna U V
   Assistant Professor, Srinivas College of Pharmacy, Mangalore, Karnataka, India
2. Fmith Celvia Miranda
   Assistant Professor, Srinivas College of Pharmacy, Mangalore, Karnataka, India
3. Poojary Avirat Vishwanat
   Student, Srinivas College of Pharmacy, Mangalore, Karnataka, India
4. Swasthika S
   Student, Srinivas College of Pharmacy, Mangalore, Karnataka, India
5. Vaishnavi V Krishna
   Student, Srinivas College of Pharmacy, Mangalore, Karnataka, India
6. Vanditha
   Student, Srinivas College of Pharmacy, Mangalore, Karnataka, India
7. Vijetha
   Student, Srinivas College of Pharmacy, Mangalore, Karnataka, India
8. AR Shabaraya
   Principal and Director, Srinivas College of Pharmacy, Valachil, Post Farangipete, Mangalore, Karnataka, India-574143.

Abstract

Aim and Background: This study delves into the exploration of natural anthelmintics to address helminthiasis, a widespread infectious disease caused by parasitic worms. Leveraging the historical use of plants in phytotherapy, the research focuses on the ethanolic extract of leaves of Breynia vitis-idaea for its potential anthelmintic properties. Methodology: The investigation involves phytochemical screening, earthworm bioassays, and the formulation of a child-friendly herbal jelly. Result: The study reveals promising anthelmintic efficacy in ethanolic extract of leaves of Breynia vitis-idaea , particularly at concentrations exceeding 40 mg/mL. The formulated herbal jelly, with Batch F3 exhibiting the desired attributes, offers an appealing solution for parasitic infections in children. The dark green jelly, with a pleasant odor and thick consistency, proves to be a viable alternative to traditional anthelmintic drugs. Conclusion: The study underscores the global shift towards herbal remedies, driven by their natural origin and minimal side effects. In regions with limited access to modern healthcare, the reliance on traditional practitioners and medicinal plants becomes crucial, emphasizing the need to integrate traditional wisdom with scientific validation. As the world faces evolving health challenges, embracing and further exploring the potential of herbal interventions is imperative for resilient and sustainable healthcare systems. The results of this study add to the growing body of evidence that herbal alternatives to conventional anthelmintic drugs are better, especially when it comes to genetic resistance. The study also supports using herbal remedies in healthcare. Keywords: Breynia vitis-idaea , Anthelmintic activity, Helminthiasis, Jelly.

Keywords

ethanolic extract of leaves of Breynia vitis-idaea (ELBV); Anthelmintic activity; Helminthiasis; formulation; Paediatric herbal edible jelly.

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