ASSOCIATION OF VITAMIN D DEFICIENCY WITH HYPERANDROGENISM IN FEMALES WITH POLYCYSTIC OVARIAN SYNDROME

Authors

1. Fouzia Hanif
   Not available, refer to PDF
2. Nasim Ilyas
   Not available, refer to PDF
3. Tehmina Qamar
   Not available, refer to PDF

Abstract

Objective: This study designed to assess the relationship of vitamin D status with clinical features of hyperandrogenism in the young unmarried females Study design: A case control study. The study was carried out in Gynecology and Obstetrics unit of Railway Hospital, Rawalpindi from Oct, 2014 to April, 2015. Materials and Methods: A sample of 100 diagnosed PCOS patients, age range 16-25 years with clinical features of hyperandrogenism were included in this study with their written consent. 25OH Vitamin D Total Elisa Kit was used to assess the levels of Vitamin D. The Data was analyzed by using SPSS version 21 and ANOVA test was used to assess the relationship. P value < 0.05 was considered significant. Results: Vitamin D levels were tested in PCOS patients presenting clinical features of hyperandrogenism and it is found that there is insignificant relationship present between severity of hypovitaminosis D and  hirsutism (P=0.669), acne (P=0.480) and alopecia (P=0.317) among PCOS patients. Conclusion: Although hirsutisim presents itself as the most common feature in PCOS patients (51%), but no significant relationship is found between Hypovitaminosis D and clinical features of hyperandrogenism suggesting insignificant role of vitamin D in the pathogenesis of hyperandrogenism in PCOS patients. 
 Keywords: Polycystic Ovarian Syndrome; Hyperandrogenism; Vitamin D.

Full Text

HTML full text is not available. Refer to the PDF galley.