CORRELATION OF PROLACTIN LEVELS WITH THYROID HORMONE LEVELS IN THYROID DISORDERS, INFERTILITY AND MENSTRUAL DISORDERS
Journal: International Journal of Clinical and Biomedical Research
Article type: Original Research Articles
Published: 2018-04-15
Volume: 4; Issue: 2; Pages: 12-15
ISSN: 2395-0471
Article URL: https://journals.sumathipublications.com/article/article-1784652858512-844849851
PDF: https://journals.sumathipublications.com/article/article-1784652858512-844849851.pdf
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Authors
- Shidhaye Nikhil P
Not available, refer to PDF - Pratinidhi SA
Not available, refer to PDF - Savla Khushboo S
Not available, refer to PDF - Zope RD
Not available, refer to PDF - Sontakke Alka
Not available, refer to PDF
Abstract
Introduction: Prolactin and Thyroid hormones are regulated through an interrelated pathway. The increased level of TRH in hypothyroidism stimulates the release of prolactin. Prolactin and thyroid disorders are associated in a variety of conditions. Aims: To find if any correlation exists between Prolactin and Thyroid hormone levels in thyroid disorders. Methods: It was an observational, retrospective study. Serum levels of T3, T4, TSH and Prolactin were estimated by ELISA kits. The data was collected from registers and analyzed for correlation. Results: A significant proportion of hyperprolactinemia cases are Euthyroid. Hyperprolactinemia is associated with both hypothyroidism as well as hyperthyroidism. It is more prevalent in hypothyroid cases. Prolactin has a positive correlation with TSH in both hyperthyroidism and hypothyroidism. Conclusion: Prolactin has a positive correlation with TSH in both hyperthyroidism and hypothyroidism. Both prolactin and thyroid hormone levels should be estimated in cases of infertility, menstrual disturbances and thyroid disorders. Keywords: Hyperprolactinemia; Hyperthyroidism; Hypothyroidism.
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