MYASTHENIA GRAVIS, THYMOMA, AND THYMOMECTOMY: THE CLINICAL INTERPLAY.
Journal: International Journal of Clinical and Biomedical Research
Article type: Review Articles
Published: 2018-04-15
Volume: 4; Issue: 2; Pages: 80-83
ISSN: 2395-0471
Article URL: https://journals.sumathipublications.com/article/article-1784652858526-191539298
PDF: https://journals.sumathipublications.com/article/article-1784652858526-191539298.pdf
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Authors
- Samuel Oyewole
All Saints University School of Medicine - David Adeiza Otohinoyi
All Saints Univesity School of Medicine - Akinfisoye Toluwalase
Not available, refer to PDF - Ibukun Oshobu
All Saints University School of Medicine - Ajibola Babatunde
All Saints University School of Medicine - Temidayo Abe
All Saints University School of Medicine - Esther Olunu
All Saints University School of Medicine - Adegbenro Omotuyi John Fakoya
All Saints University School of Medicine
Abstract
Myasthenia gravis is an autoimmune disorder that places patients in debilitating condition. It currently affects 14 to 20 per 100,000 population. Its pathogenesis involves the destruction of acetylcholine receptor by antibodies produced by lymphocytes in the thymus gland. Symptoms could vary from impair extraocular muscles to generalized weakness. The antibodies have also been reported to affect other muscle structure within the body such as cardiomyocytes, leading to arrhythmia episodes which could be fatal. This review is a student project and involves the assessment of myasthenia gravis and the interplay between thymoma and thymomectomy.
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