HYPOMAGNESAEMIA AND HYPOCALCAEMIA THE MAJOR MISSED OUT CLINICAL CONDITION IN THE MANAGEMENT OF DIABETES

Journal: International Journal of Clinical and Biomedical Research

Article type: Original Research Articles

Published: 2021-05-04

Volume: 7; Issue: 2; Pages: 16-22

ISSN: 2395-0471

DOI: 10.31878/ijcbr.2021.72.04

Article URL: https://journals.sumathipublications.com/article/article-1784653631343-517173963

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Authors

  1. Divya S
    Not available, refer to PDF
  2. Fahima Sheerin SMH
    1Department of Medical Laboratory Technology, Loyola College, Nungambakkam Chennai, India
  3. Chindhiha S
    1Department of Medical Laboratory Technology, Loyola College, Nungambakkam Chennai, India
  4. Suganthi M
    Post Doctoral Fellow, Centre for Biotechnology, Anna University, Guindy Chennai, India
  5. Sherafin Vincy
    Department of Medical Laboratory Technology, Loyola College, Nungambakkam Chennai, India
  6. Chandrasekar M
    Department of Medical Laboratory Technology, Loyola College, Nungambakkam Chennai, India
  7. Dr Selvakumar Kandaswamy
    The Tamilnadu MGR Medical University

Abstract

Magnesium (Mg) and Calcium (Ca) is one of the essential factors for the insulin to get released from the pancreatic cell. To evaluate the relation of hypomagnesemia and hypocalcaemia in the glycaemic control and to analyse the importance of both Mg and Ca in the insulin secretion mechanism. The study was conducted in the laboratory department, Billroth hospitals. A total of 239 individuals were selected for this study, HbA1c level, serum magnesium and calcium were assessed for all the individuals and in addition to this serum electrolytes were also checked. Out of 239 individuals, 79 were found out as uncontrolled diabetic by calculating HbA1c as a gold standard, males are higher in ratio compared to female. By studying serum magnesium and calcium level, hypocalcaemia is present in more individuals and females (31%) are much prone to both than males (20%). The different correlation was also analysed for hypomagnesemia and hypocalcaemia. The electrolytes like sodium (Na) and potassium (K) was analysed, females are highly affected by electrolyte imbalance but in hypomagnesemia diabetic individuals the males are high in electrolyte imbalance. Since Mg and Ca plays a vital role in insulin synthesis, secretion, repair, and the alteration, along with the hypoglycaemic agents the supplementation of magnesium or calcium could be suggested via, dietary or drug supplements. In addition to this, regular monitoring of electrolytes is essential to maintain fluid balance.

Keywords

Magnesium, calcium, insulin secretion, uncontrolled diabetes, electrolytes

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