Introduction to Antimalarial Drugs Antimalarial drugs play a critical role in preventing and treating malaria, a life-threatening illness caused by Plasmodium parasites carried by infected Anopheles mosquitoes. This comprehensive guide delves into the classifications, mechanisms of action, pharmacological properties, applications, side effects, and potential drug interactions of antimalarial medications. Let’s explore this further! Please refer…
Introduction to Dyslipidemias Drugs used for dyslipidemias or Antihyperlipidemic drugs play a critical role in managing lipid disorders, which are significant risk factors for cardiovascular diseases such as coronary heart disease (CHD). Over 650,000 people die of CHD in the US alone every year, and a 1% reduction in serum cholesterol has been associated with…
Introduction to Congestive Cardiac Failure Congestive cardiac failure, also known as congestive heart failure (CHF), is a complex clinical syndrome that impairs the pumping capacity of the heart. It can be caused by various heart conditions, leading to symptoms like shortness of breath, persistent coughing, swelling in the legs, ankles and feet, and rapid weight…
Introduction Antimicrobial stewardship programs (ASPs) have emerged as a crucial component in the fight against antimicrobial resistance (AMR). This resistance has been identified as a significant global health threat by the World Health Organization [1]. The goal of ASPs is to optimize antibiotic use in healthcare settings, thereby improving patient outcomes, reducing microbial resistance, and…
In the realm of pharmacology, the last century has witnessed a significant evolution in scientific research. This evolution has been driven by meticulously designed studies and continuous technological advancements that have enabled the measurement and analysis of biological samples and subjects. As a result, our understanding of biological systems has expanded exponentially. The term ‘in…
Introduction to Antimicrobial Stewardship Antimicrobial stewardship (AMS) is a systematic approach aimed at promoting the appropriate use of antimicrobials to improve patient outcomes, reduce microbial resistance, and decrease the spread of infections caused by multidrug-resistant organisms[1]. The Importance of Antimicrobial Stewardship AMS is crucial in the fight against antimicrobial resistance (AMR), a global health threat…
Introduction to SAR The field of medicinal chemistry is replete with examples of how subtle changes in the molecular structure of a compound can have profound effects on its biological activity. This concept, known as the structure-activity relationship (SAR), is a fundamental principle in drug discovery and development. In this article, we will delve into…
Introduction Antiepileptic drugs (AEDs) are medications used to treat epilepsy, a neurological disorder characterized by recurrent seizures. There are several classes of AEDs, each with different mechanisms of action, therapeutic uses, and adverse effects. In this answer, we will discuss the classification of AEDs, along with examples of drugs in each class, their mechanism of…
Introduction Antiparkinsonian drugs are a group of medications used to treat the symptoms of Parkinson’s disease, a neurodegenerative disorder characterized by tremors, rigidity, and bradykinesia. These drugs work by either increasing dopamine levels in the brain or blocking the effects of acetylcholine. Here is a classification of antiparkinsonian drugs along with examples, their mechanism of…
Sedative-hypnotics are a class of drugs that work on the central nervous system (CNS) to produce a calming or drowsy effect and are often prescribed for insomnia, anxiety, and seizure disorders. They can be classified into three main categories: benzodiazepines, barbiturates, and Z-drugs (non-benzodiazepine hypnotics). Here’s a brief overview of these classes, along with some…