Emergency & First Aid: Anaphylaxis and Using an EpiPen
Introduction Definition and Overview Anaphylaxis is an acute, life‑threatening systemic hypersensitivity reaction that involves the rapid release of mediators from mast cells and basophils. Clinical manifestations typically include cutaneous signs (urticaria, angioedema), respiratory compromise (bronchospasm, laryngeal edema), cardiovascular instability (hypotension, tachycardia), and gastrointestinal disturbance (vomiting, diarrhea). Rapid recognition and intervention are essential to avert progression…